For an oocyte to be Prepared for fertilization and advancement into an embryo, the correct list of genes needs to be turned on. Namekawa suspected that this pre-programming on the oocyte genome comes about in numerous phases — the main a single starting off across the time a woman is born. He thought that chromatin remodeling proteins did Substantially of this get the job done, by shifting spools all over.

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Function by Namekawa and Munakata indicates that a vital function takes place round the time of start: the nascent egg cells enter a Keeping pattern, with their DNA exactly packaged and primed for fertilization later in life.

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